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The aromatase inhibitor letrozole enhances the effect of doxorubicin and docetaxel in an MCF7 cell line model

Mary O’Neill1, Fiona E.M. Paulin1, Julie Vendrell1, Clinton W. Ali2, Alastair M. Thompson1,3* 1Dundee Cancer Centre, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland,...

Bringing together all aspects of cancer research, prevention and treatment. A report from the 8th NCRI Cancer Conference

Dimitar Trifonov BioDiscovery, Dundee Science Press, Dundee, Scotland bstract The 8th NCRI Cancer Conference took place from 4th until 7th of November 2012 in the BT Convention Centre, Liverpool, UK....

Advocating the need of a systems biology approach for personalised prognosis and treatment of B-CLL patients

Hemanth Tummala1, Alexey Goltsov1, Hilal S Khalil1, Anne Sproul2, Fiona Scott2, Vanio Mitev3, Nikolai Zhelev1 1School of Contemporary Sciences, Kydd Building, University of Abertay Dundee,...

Chromosome rearrangements in sublines of human embryonic stem cell lines hESM01 and hESM03

Tatyana V. Karamysheva1, Мaria А. Prokhorovich1,3, Maria A. Lagarkova2, Sergey L. Kiselev2, Thomas Liehr4, Nikolay B. Rubtsov1,3 1Institute of Cytology and Genetics, SB RAS, Novosibirsk,...

Skeletal muscle: novel and intriguing characteristics as a secretory organ

Wataru Aoi1, Kunihiro Sakuma2 1Laboratory of Health Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, 1-5 Hangi-cho Shimogamo, Sakyo-ku, Kyoto, Japan 2Health Science...

Herpetofauna in the city of Blagoevgrad, south-western Bulgaria

Alexander Pulev, Lidia Sakelarieva Department of Geography, Ecology and Environmental Protection, Faculty of Mathematics and Natural Sciences, South-West University "Neofit Rilski", 66 Ivan Mihailov Street,...

Modelling c-Abl Signalling in Activated Neutrophils: The Anti-inflammatory Effect of Seliciclib

Robert C. Jackson1, Tomas Radivoyevitch2 1Pharmacometrics Ltd., Cambridge, UK 2Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, USA Abstract When mammalian tissues are infected by...

Switching on p53: an essential role for protein phosphorylation?

Jayne Loughery, David Meek Division of Cancer Research, Medical Research Institute, Clinical Research Centre/Jacqui Wood Cancer Centre, The University of Dundee, James Arrott Drive, Ninewells...

Modulation of immune responses by the tumor suppressor p53

Julie Lowe, Maria Shatz, Michael A. Resnick, Daniel Menendez Chromosome Stability Section, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, National Institutes of...

Distinct target genes and effector processes appear to be critical for p53-activated responses to acute DNA damage versus p53-mediated tumour suppression

Liz J Valente1, 2, Andreas Strasser1, 2 1The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia 2Department of Medical...
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