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NRF2 inhibition causes repression of ATM and ATR expression leading to aberrant DNA Damage Response

Hilal S. Khalil, Yusuf Deeni School of Science, Engineering and Technology, Abertay University, Dundee, DD1 1HG, United Kingdom Abstract Nuclear factor (erythroid-derived 2)-like 2 (NRF2) is a...

Small molecules and human cardiomyogenesis: Is there a bottleneck in current research?

Dimitar Trifonov BioDiscovery, Dundee Science Press, Dundee, Scotland Abstract Human pluripotent stem cell derived cardiomyocytes (hPSC-derived CMs) have a vast potential in drug discovery, disease modeling and...

Human pluripotent stem-cell-derived cardiomyocytes in cardiovascular drug discovery and development

Kirsty Lewis, Kerry Falconer CMCBR, Abertay Uiversity, Dundee, Scotland, Bell Street, Dundee,UK, DD1 1HG Abstract Cardiovascular disease (CVD) is an alarming health problem responsible for a large...

APOE4, oxidative stress and decreased repair capacity – a no-brainer. Faulty lipid metabolism and increased levels of oxidative damage may be risk factors in...

Ashima Nayyar1, Lubomira Chakalova2 1CMCBR, School of Science Engineering and Technology, Abertay University, Dundee DD1 1HG, UK 2Institute of Molecular Biology, Bulgarian Academy of Sciences, Acad....

Blood-Based Gene Expression in children with Autism spectrum disorder

Hristo Y. Ivanov1, Vili K. Stoyanova1,2, Nikolay T. Popov3, M. Bosheva1,2, Tihomir I. Vachev1,4 1Department of Pediatrics and Medical Genetics, Medical University, Plovdiv Vasil Aprilov...

A de novo microdeletion 2p24.3-25.1 identified in a girl with global development delay

Hristo Y. Ivanov1#, Vili K. Stoyanova1,2#, Radoslava Vazharova3,4#, Aleksandar Linev2, Ivan Ivanov1,2, Samuil Ivanov4, Lubomir Balabanski4, Draga Toncheva4,5 1Medical University - Plovdiv, Department of Pediatrics...

An old wives’ tale. Reproductive outcomes in pregnant women aged 35 or older: the role of individual repair capacity

Petkova R1, Dimitrova V2, Zhelev N3, Chakarov S4 1Scientific Technological Service (STS) Ltd., Sofia, Bulgaria 2State University Hospital "Maichin Dom", Medical University of Sofia, Sofia, Bulgaria 3CMCBR,...

Sensational and Discreet: The Best London Escort Experiences

When it comes to experiencing the best London escort services, discerning clients seek a blend of sensuality, discretion, and exceptional companionship. London, a city...
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